Amateka ya Platelet ikize Plasma (PRP)

Kubijyanye na Platelet ikize Plasma (PRP)

Plasma ikungahaye kuri plasma (PRP) ifite agaciro kagereranya kuvura ingirabuzimafatizo kandi kuri ubu ni imwe mu miti ivura ibyiringiro mu buvuzi bushya.Irakoreshwa cyane mubuvuzi butandukanye, harimo kwisiga dermatology, ortopedie, ubuvuzi bwa siporo no kubaga.

Mu 1842, havumbuwe izindi nyubako zitari selile zitukura n'umweru zavumbuwe mu maraso, byatunguye abo mu gihe cye.Julius Bizozero niwe wambere wavuze amazina mashya ya platine "le piastrine del sangue" - platine.Mu 1882, yasobanuye uruhare rwa platine muri coagulation muri vitro n'uruhare rwabo muri etiologiya ya trombose muri vivo.Yasanze kandi inkuta z'amaraso zibuza gufata platine.Wright yateye imbere cyane mugutezimbere tekinike yubuvuzi bushya hamwe no kuvumbura macrokaryocytes, ibanziriza platine.Mu ntangiriro ya 1940, abaganga bakoresheje insoro “insimburangingo” igizwe n'impamvu zo gukura hamwe na cytokine kugira ngo bakire ibikomere.Gukiza ibikomere byihuse kandi neza nibyingenzi kugirango bigerweho muburyo bwo kubaga.Kubwibyo, Eugen Cronkite n'abandi.yatangije uruvange rwa trombine na fibrin mubikorwa byuruhu.Ukoresheje ibice byavuzwe haruguru, hafashwe ingamba zihamye kandi zihamye za flap, bigira uruhare runini muri ubu bwoko bwo kubaga.

Mu ntangiriro z'ikinyejana cya 20, abaganga babonye ko byihutirwa kwinjiza amaraso kugira ngo bavure trombocytopenia.Ibi byatumye habaho iterambere muburyo bwo gutegura platine.Kwiyongera hamwe na platine yibanze birashobora kwirinda kuva amaraso kubarwayi.Muri icyo gihe, abaganga n’abaganga ba laboratoire bagerageje gutegura ibinini bya platine kugirango baterwe.Uburyo bwo kubona intungamubiri bwateye imbere byihuse kandi bwateye imbere ku buryo bugaragara, kubera ko amasahani yitaruye ahita atakaza imbaraga bityo akaba agomba kubikwa kuri 4 ° C kandi agakoreshwa mu masaha 24.

Ibikoresho nuburyo

Mu myaka ya za 1920, citrate yakoreshejwe nka anticoagulant kugirango ibone platine.Iterambere mu itegurwa rya platine ryihuta mu myaka ya za 1950 na 1960 igihe hashyizweho ibikoresho byamaraso byoroshye.Ijambo "plasma ikungahaye kuri platel" ryakoreshejwe bwa mbere na Kingsley n'abandi.muri 1954 yerekeza kuri platine isanzwe ikoreshwa muguterwa amaraso.Banki ya mbere yamaraso PRP yakozwe yagaragaye mu myaka ya za 1960 ikamenyekana muri za 1970.Mu mpera za 1950 na 1960, hakoreshejwe “paki ya platel ya EDTA”.Igice kirimo umufuka wa pulasitike ufite amaraso ya EDTA yemerera platine kwibanda hamwe na centrifugation, igakomeza guhagarikwa muri plasma nkeya nyuma yo kubagwa.

Igisubizo

Bikekwa ko ibintu bikura (GFs) nibindi bintu bya PRP bisohoka muri platine kandi bigira uruhare mubikorwa byayo.Iyi hypothesis yemejwe mu myaka ya za 1980.Biragaragara ko platine irekura molekile ya bioactive (GFs) kugirango isane ingirangingo zangiritse, nk'ibisebe by'uruhu.Kugeza ubu, ubushakashatsi buke bwiga kuri iki kibazo bwakozwe.Kimwe mu bintu byize cyane muriki gice ni uguhuza PRP na aside hyaluronic.Icyorezo cya Epidermal (EGF) cyavumbuwe na Cohen mu 1962. GF yakurikiyeho ni ibintu byakuze biva mu maraso (PDGF) mu 1974 hamwe n’ikura ry’imitsi iva mu mitsi (VEGF) mu 1989.

Muri rusange, iterambere mubuvuzi naryo ryatumye iterambere ryihuta mubikorwa bya platine.Mu 1972, Matras yakoresheje bwa mbere platine nk'ikidodo kugira ngo amaraso ya homeostasis mu gihe cyo kubagwa.Byongeye kandi, mu 1975, Oon na Hobbs ni abahanga ba mbere bakoresheje PRP mu buvuzi bwubaka.Mu 1987, Ferrari n'abandi babanje gukoresha plasma ikungahaye kuri platel nk'isoko ya autologique yo guterwa amaraso mu kubaga umutima, bityo bigabanya gutakaza amaraso mu mikorere idahwitse, guhungabana kw'amaraso yo gutembera kwa periferiya, no gukoresha ibikomoka ku maraso.

Mu 1986, Knighton n'abandi.ni abahanga mu bya mbere basobanuye protocole ikungahaye kuri platel hanyuma bayita autologique platelet-ibikomere bikiza ibikomere (PDWHF).Kuva hashyirwaho protocole, tekinike yagiye ikoreshwa mubuvuzi bwiza.PRP yakoreshejwe mubuvuzi bushya kuva mu mpera za 1980.

Usibye kubaga muri rusange no kubaga umutima, kubaga maxillofacial ni akandi gace PRP yamenyekanye mu ntangiriro ya za 90.PRP yakoreshejwe mugutezimbere ibihano muburyo bwo kwiyubaka.PRP nayo yatangiye gushyirwa mubikorwa mubuvuzi bw'amenyo kandi yakoreshejwe kuva mu mpera za 90 mugutezimbere guhuza amenyo no guteza imbere amagufwa.Byongeye kandi, fibrin glue yari ibintu bizwi bifitanye isano byatangijwe icyo gihe.Ikoreshwa rya PRP mubuvuzi bw'amenyo ryarushijeho gutera imbere hifashishijwe fibrin ikungahaye kuri platine (PRF), intungamubiri ya platine idasaba kongeramo imiti igabanya ubukana, na Choukroun.

PRF yarushijeho gukundwa cyane mu ntangiriro ya za 2000, hamwe n’ibisabwa byiyongera mu buryo bwo kuvura amenyo, harimo kuvugurura ingirabuzimafatizo ya hyperplastic gingival hamwe nudusembwa twa parontontal, gufunga ibikomere bya palatale, kuvura indwara ya gingival, no gukuramo amaboko.

Muganire

Anitua mu 1999 yasobanuye ikoreshwa rya PRP mugutezimbere amagufwa mugihe cyo guhana plasma.Nyuma yo kureba ingaruka nziza zokuvurwa, abahanga bakoze ubushakashatsi kuri iki kibazo.Inyandiko ze zakurikiyeho zavuze ingaruka z'aya maraso ku bisebe by'uruhu bidakira, gutera amenyo, gukira imitsi, no gukomeretsa siporo.Imiti myinshi ikora PRP, nka calcium chloride na bovine trombine, yakoreshejwe kuva 2000.

Bitewe nibintu byiza byayo, PRP ikoreshwa muri ortopedie.Ibyavuye mu bushakashatsi bwimbitse bwimbitse ku ngaruka ziterwa no gukura kwingirangingo zumuntu zasohotse mu 2005. Ubu ubuvuzi bwa PRP bukoreshwa mu kuvura indwara zangirika no guteza imbere gukira kw'imitsi, ligaments, imitsi na karitsiye.Ubushakashatsi bwerekana ko gukomeza gukundwa nuburyo bukoreshwa mu magufwa bishobora no kuba bifitanye isano no gukoresha PRP kenshi naba star ba siporo.Mu mwaka wa 2009, hasohotse ubushakashatsi bw’inyamaswa bwemeza hypothesis ivuga ko PRP yibanda ku kunoza imitsi.Uburyo bwibanze bwibikorwa bya PRP muruhu ni ingingo yubushakashatsi bwimbitse.

PRP yakoreshejwe neza muri cosmetic dermatology kuva 2010 cyangwa mbere yaho.Nyuma yo gutera inshinge PRP, uruhu rusa nkuruto kandi rwihuta, guhinduka hamwe nibara byateye imbere cyane.PRP nayo ikoreshwa mugutezimbere imikurire.Hariho ubwoko bubiri bwa PRP muri iki gihe bukoreshwa mu kuvura imikurire yimisatsi - plasma ikungahaye kuri plasma (A-PRP) hamwe na plasma ikungahaye kuri platine (AA-PRP).Ariko, Abanyamahanga n'abandi.yerekanye ko ubucucike bwimisatsi nibipimo byo kubara umusatsi bishobora kunozwa mugutera A-PRP.Byongeye kandi, byagaragaye ko gukoresha imiti ya PRP mbere yo guhinduranya umusatsi bishobora kongera imikurire yimisatsi ndetse nubwinshi bwimisatsi.Byongeye kandi, mu mwaka wa 2009, ubushakashatsi bwerekanye ko gukoresha imvange ya PRP n’ibinure bishobora guteza imbere imiti y’amavuta no kubaho, ibyo bikaba bishobora kongera umusaruro wo kubaga plastique.

Ibyavuye mu bushakashatsi bwakozwe na Cosmetic Dermatology byerekana ko guhuza imiti ya PRP na CO2 bishobora kugabanya inkovu za acne cyane.Mu buryo nk'ubwo, PRP na microneedling byatumye habaho imigozi myinshi ya kolagen mu ruhu kuruta PRP yonyine.Amateka ya PRP ntabwo ari mugufi, kandi ibyagaragaye bijyanye niki gice cyamaraso ni ngombwa.Abaganga n’abahanga barimo gushakisha uburyo bushya bwo kuvura.Nuburyo, PRP ikoreshwa mubice byinshi byubuvuzi, harimo nabagore, urologiya, nubuvuzi bwamaso.

Amateka ya PRP afite nibura imyaka 70.Kubwibyo, uburyo bwashizweho neza kandi burashobora gukoreshwa cyane mubuvuzi.

Ibiri muri iyi ngingo byongeye gusubirwamo, kandi ntidutanga ingwate iyo ari yo yose cyangwa yerekana ko ari ukuri, kwiringirwa cyangwa kuzuza ibikubiye muri iyi ngingo, kandi ntabwo dushinzwe ibitekerezo by'iyi ngingo, nyamuneka ubyumve.）