Plasma ikungahaye kuri Plasma (PRP) kuri Andorogenetike Alopecia (AGA)

Androgeneque alopecia (AGA), ubwoko bukunze guta umusatsi, ni indwara igenda itera umusatsi itangira mubyangavu cyangwa nyuma yubugimbi.Umubare w'abagabo mu gihugu cyanjye ni 21.3%, naho umubare w'abagore ni 6.0%.Nubwo intiti zimwe zasabye umurongo ngenderwaho mu gusuzuma no kuvura alopeciya ya androgeneque mu Bushinwa mu bihe byashize, bibanda cyane ku gusuzuma no kuvura AGA, kandi ubundi buryo bwo kuvura burabura.Mu myaka yashize, hibandwa ku buvuzi bwa AGA, hagaragaye uburyo bushya bwo kuvura.

Indwara ya Etiologiya na Pathogenez

AGA ni indwara ya polygenic recessive disorder.Ubushakashatsi bw’ibyorezo by’imbere mu gihugu bwerekana ko 53.3% -63,9% by’abarwayi ba AGA bafite amateka y’umuryango, kandi umurongo wa ba se urenze cyane umurongo w’ababyeyi.Ubushakashatsi bwakozwe kuri genome yose hamwe no gushushanya amakarita byagaragaje ingirabuzimafatizo nyinshi, ariko ingirabuzimafatizo zazo ntizamenyekana.Ubushakashatsi buriho bwerekana ko andorogene igira uruhare rukomeye mugutera indwara ya AGA;ibindi bintu birimo gutwika umusatsi, kongera umuvuduko wubuzima, guhangayika no guhangayika, hamwe nubuzima bubi no kurya nabi bishobora kongera ibimenyetso bya AGA.Androgène mubagabo ahanini ituruka kuri testosterone isohoka na testes;andorogene mu bagore ahanini ituruka kuri synthesis ya adrenal cortex hamwe nuduce duto duto two mu ntanga ngore, androgène ni androstenediol, ishobora guhindurwamo testosterone na dihydrotestosterone.Nubwo andorogene ari ikintu cyingenzi mu gutera indwara ya AGA, urwego rwa androgene ruzenguruka mu barwayi hafi ya bose ba AGA rugumaho ku rwego rusanzwe.Ubushakashatsi bwerekanye ko ingaruka za andorogene ku musatsi ushobora kwandura ziyongera bitewe n’imvugo ya androgene yakira gene imvugo hamwe na / cyangwa kwiyongera kwubwoko bwa II 5α reductase gene mumisatsi yo mu gace ka alopecia.Kuri AGA, uturemangingo twa dermal selile yumusatsi ushobora kwandura harimo ubwoko bwihariye bwa II 5α reductase, bushobora guhindura androgène testosterone ikwirakwira mukarere ka maraso na dihydrotestosterone muguhuza reseptor yo mu nda.Gutangiza urukurikirane rw'ibisubizo biganisha kuri miniaturizasi igenda itera imisatsi no guta umusatsi.

Ibyerekanwe kwa Clinical hamwe nibyifuzo byo kuvura

AGA ni ubwoko bwa alopecia idakomeretsa ubusanzwe itangira mugihe cyubwangavu kandi ikarangwa no kunanuka gahoro gahoro ya diametre yimisatsi, gutakaza ubwinshi bwimisatsi, na alopeciya kugeza ubwo umusatsi utandukanye, ubusanzwe uherekezwa nibimenyetso byiyongera ryamavuta yo mumutwe.

Gusaba PRP

Ubunini bwa platine buhwanye nubunini bwikubye inshuro 4-6 mumaraso yose.PRP imaze gukora, α granules muri platine izarekura ibintu byinshi byikura, harimo gukura kwa platine, guhindura ibintu bikura-β, insuline imeze nkikura, icyorezo cya epidermal niterambere ryimitsi iva mu mitsi, nibindi. Uruhare yo guteza imbere imikurire yimisatsi, ariko uburyo bwihariye bwibikorwa ntibusobanutse neza.Imikoreshereze ni ugutera PRP mugace ka dermis yumutwe wumutwe mugace ka alopecia, rimwe mukwezi, kandi inshinge zihoraho inshuro 3 kugeza kuri 6 zishobora kubona ingaruka runaka.Nubwo ubushakashatsi butandukanye bw’amavuriro haba mu gihugu ndetse no mu mahanga bwemeje mbere na mbere ko PRP igira ingaruka runaka kuri AGA, nta mahame amwe amwe yo gutegura PRP, bityo igipimo cyiza cyo kuvura PRP ntabwo ari kimwe, kandi gishobora gukoreshwa nk'umufasha. uburyo bwo kuvura AGA muriki cyiciro.

Ibiri muri iyi ngingo byongeye gusubirwamo, kandi ntidutanga ingwate iyo ari yo yose cyangwa yerekana ko ari ukuri, kwiringirwa cyangwa kuzuza ibikubiye muri iyi ngingo, kandi ntabwo dushinzwe ibitekerezo by'iyi ngingo, nyamuneka ubyumve.）