Indwara ya rinite yibanze (1Ry AR) nindwara idakira yizuru irangwa no gutakaza imikorere yimitsi ya mucociliary, kuba hari ururenda rukomeye hamwe nigituba cyumye, biganisha ku mpumuro mbi isanzwe, mubisanzwe byombi.Umubare munini wokuvura wagerageje, ariko haracyari ubwumvikane buke bwo kuvura igihe kirekire.Intego yubu bushakashatsi ni ugusuzuma agaciro ka plasma ikungahaye kuri platel nkibitera ibinyabuzima bigamije gukiza indwara ya rinite yibanze.
Umwanditsi yashyizemo abantu 78 bose basuzumwe indwara ya rinite yibanze.Itsinda A (imanza) hamwe n’abarwayi bafite platine mbi bakorewe endoskopi yizuru, Ikizamini cya Sino Nasal Ikizamini-25, ikizamini cya saccharin cyo gusuzuma igipimo cya ciliary ciliary, na plasma muri biopsy urugero rwa B (kugenzura) ukwezi 1 n'amezi 6 mbere yo kubisaba ya platine ikungahaye kuri plasma.
Ibimenyetso byakunze kugaragara ku barwayi bose bo mu itsinda A mbere yo gutera inshinge za plasma ikungahaye kuri platine harimo ibisebe byo mu mazuru, byerekanaga iterambere rya endoskopi kandi bikagabanya indwara, hamwe na 36 (92,30%);foetor, 31 (79.48%);Kubuza amazuru, 30 (76,92%);Gutakaza impumuro, 17 (43.58%);Epistaxis, 7 (17,94%) kugeza ku mazuru, 9 (23.07%);Ibirenge, 13 (33.33%);Umuvuduko w'amazuru, 14 (35.89%);Gutakaza impumuro, 13 (33.33%);Kandi epistaxis, 3 (7,69%), nyuma y'amezi 6, ibi bigaragarira mu kugabanuka kw'amanota ya Sino Nasal Ibisubizo-25, wagereranije 40 mbere ya plasma ikungahaye kuri platine hanyuma ukagabanuka ukagera kuri 9 nyuma y'amezi 6.Mu buryo nk'ubwo, igihe cyo gukuraho mucociliary cyaragabanutse cyane nyuma yo guterwa plasma ikungahaye kuri platel;Ikigereranyo cyambere cyo gutwara saccharin igihe cyo gutwara cyari amasegonda 1980, kandi cyaragabanutse kugera kumasegonda 920 nyuma y'amezi 6 nyuma yo guterwa plasma ikungahaye kuri platel.
Gukoresha plasma ikungahaye kuri plasma nkibikoresho byibinyabuzima bishobora kuba uburyo bushya bwibasirwa cyane bushobora gusana neza imirire mibi yimitsi binyuze mubushakashatsi bwimbitse.
Hariho uburyo bune bwingenzi bwo kuvura indwara ya rinite ya Atrophique: kugabanya umwobo wizuru hamwe nibintu bitandukanye hamwe nogushiramo, guteza imbere imitsi isanzwe ikoresheje kubagwa kwa Yangasi ya kera cyangwa yahinduwe, gusiga amavuta yizuru, cyangwa kunoza imiyoboro yamaraso yizuru.Cavity.Ubundi buryo bwinshi bwo kuvura bwageragejwe, harimo kuvomera amazuru no gutemba, glucose glycerol ibitonyanga byamazuru, paraffine yamazi, estradiol mumavuta yintoki, umuti urwanya ozaena, antibiotike, fer, zinc, proteyine, inyongera za vitamine, vasodilator, prostate, inkingo, ibivamo insina. cyangwa acetylcholine, hamwe na pilocarpine cyangwa idafite.Ariko, imikorere yubu buryo iratandukanye.Mubikorwa byubuvuzi, kwoza umwobo wizuru ukoresheje spray yamazuru nuburyo bukoreshwa cyane mukuvura ibimenyetso byindwara ya rinite ya atrophique, kuko ishobora gutobora imitsi yizuru kandi ikarinda gufatwa.
Muri ubwo buryo bwavuzwe haruguru, uburyo bwiza bwo kubaga Yang bwagaragaye ko ari uburyo bwiza kandi burambye bwo kuvura indwara ya rinite.Ariko, guhumeka umunwa kuvamo bishobora gutera abarwayi nabi cyane.Amavuta hamwe ninyongera byagaragaye ko bifite ingaruka nke kandi zigihe gito.Kubwibyo, ubundi buryo bwo guteza imbere imitsi yizuru cyangwa angiogenezi byakozwe.
PRPigizwe nubushakashatsi bwa plasma burenze ubwinshi bwa platine mumaraso yose.PRP itezimbere ibintu bigira ingaruka kumikurire yinyama, gutandukana, no gukira inkovu, nka platine ikomoka kumikurire, guhindura ibintu bikura, gukura kwa fibroblast, gukura kwa endoteliyale, hamwe niterambere rya insuline.Kubwibyo, PRP byagaragaye ko ifite ibisubizo byiza byemewe mubushakashatsi bwubuvuzi butandukanye, biteza imbere gukira ibikomere no kuvugurura ingirabuzimafatizo, harimo no mubijyanye na otolaryngologiya.By'umwihariko, byavuzwe ko PRP igira akamaro mu kunoza imiterere ya tympanic membrane, umugozi wijwi hamwe n imitsi yo mumaso, ndetse no gukira nyuma yo kubagwa myringoplasty cyangwa endoscopique sinus.Byongeye kandi, ubushakashatsi bwikigereranyo bwakozwe mu myaka mike ishize kugirango bavure rinite ya atrophike hamwe no gutera inshinge za PRP lipid.Byongeye kandi, PRP ikoresha amaraso ya autologique kandi ntigira reaction ya allergique cyangwa immunite.Irashobora gutegurwa byoroshye muminota mike binyuze muri centrifugation ebyiri.
Muri ubu bushakashatsi, twakoze iperereza ku gutera inshinge PRP muri mucosa atrophique nasose, byateje imbere mucosal cilia no kwerekana ibimenyetso mugihe cy'amezi 6 yakurikiranwe, cyane cyane kubarwayi bakiri bato, ibisubizo bigaragara cyane ugereranije nitsinda ryabasaza.Mubihe byinshi bya rhinite ya Atrophique, harimo na rinite ishaje, ururenda rugabanuka.Kubwibyo, kubyimba kwa mucinous biganisha ku gutinda gukuraho amazuru ya cilia.Kuzuza amazi binyuze muri saline ya saline bizagira ingaruka kumiterere ya mucus viscous viscous, kandi kuvanaho mucosa mucosa cilia bizasubizwa kurwego runaka.Ariko, uruhare rwamazuru yizuru mugukemura ibimenyetso byizuru birashobora kuba bike.Kubwibyo, nubwo amazi yizuru yama conservateur ashobora kandi kongera uburibwe bwa mucociliary, ubu buryo bwo kuvura ntabwo bwahinduye neza ibimenyetso byizuru.Byongeye kandi, gutera amazuru no kuhira bisaba saline physiologique nibikoresho byihariye, kandi bigomba gukorwa buri gihe kugirango bigabanye ibimenyetso.Ibinyuranye, inshinge PRP isaba gusa inshinge imwe kugirango igere kubisubizo byiza.Nyuma yo guterwa, ingano ya turbinate ihita yiyongera.Ariko, mugusura ubutaha kwa muganga (nyuma y'ibyumweru 2), nta tandukaniro ryabaye mubunini n'imiterere ya turbinite yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no guterwa inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Gutera amazuru no kuhira bisaba saline physiologique nibikoresho byihariye, kandi bigomba gukorwa buri gihe kugirango bigabanye ibimenyetso.Ibinyuranye, inshinge PRP isaba gusa inshinge imwe kugirango igere kubisubizo byiza.Nyuma yo guterwa, ingano ya turbinate ihita yiyongera.Ariko, mugusura ubutaha kwa muganga (nyuma y'ibyumweru 2), nta tandukaniro ryabaye mubunini n'imiterere ya turbinite yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no guterwa inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Gutera amazuru no kuhira bisaba saline physiologique nibikoresho byihariye, kandi bigomba gukorwa buri gihe kugirango bigabanye ibimenyetso.Ibinyuranye, inshinge PRP isaba gusa inshinge imwe kugirango igere kubisubizo byiza.Nyuma yo guterwa, ingano ya turbinate ihita yiyongera.Ariko, mugusura ubutaha kwa muganga (nyuma y'ibyumweru 2), nta tandukaniro ryabaye mubunini n'imiterere ya turbinite yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no guterwa inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Gutera PRP bisaba inshinge imwe gusa kugirango ugere kubisubizo byiza.Nyuma yo guterwa, ingano ya turbinate ihita yiyongera.Ariko, mugusura ubutaha kwa muganga (nyuma y'ibyumweru 2), nta tandukaniro ryabaye mubunini n'imiterere ya turbinite yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no guterwa inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Gutera PRP bisaba inshinge imwe gusa kugirango ugere kubisubizo byiza.Nyuma yo guterwa, ingano ya turbinate ihita yiyongera.Ariko, mugihe cyo gusura kwa muganga (nyuma y'ibyumweru 2), nta tandukaniro ryabaye mubunini n'imiterere ya turbinite yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no gutera inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Nta tandukaniro riri mubunini n'imiterere ya turbinate yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no gutera inshinge bifatwa nkibidakwiye.Byongeye kandi, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza ibyiyumvo byurwego rwamarangamutima, byerekana ko ingaruka ya placebo itari ikomeye mubice runaka.Nta tandukaniro riri mubunini n'imiterere ya turbinate yo hasi.Kubwibyo, kwiyongera kwigihe gito kwijwi ryatewe no gutera inshinge bifatwa nkibidakwiye.Mubyongeyeho, nkuko bigaragara mu isesengura rya sub domaine ya SNOT-22, nta terambere ryagaragaye ryagaragaye mu marangamutima y’abarwayi batewe inshinge PRP.Ibisubizo ntabwo byajyanye no kunoza amarangamutima ya sub domaine, byerekana ko ingaruka ya placebo itari ikomeye muburyo runaka.
Ububabare budashira hamwe nibimenyetso bifitanye isano na rinite ya atrophique ntabwo bikomeye mubuvuzi.Kubwibyo, igihombo cyimibereho nubukungu ntigisuzugurwa.Nyamara, ukurikije abarwayi nyabo, ni indwara ikomeye.Byongeye kandi, hamwe no gusaza kw'abaturage, umubare w'abarwayi barwaye rinite ya senile uragenda wiyongera cyane.Niyo mpamvu, ni ngombwa cyane gutanga ubuvuzi bukwiye bwa rinite ya Atrophique, harimo na rinite ishaje.
Intego yubu bushakashatsi ni ugutanga uburyo bushya bwo kuvugurura uburyo bwo kuvura indwara ya rinite ya Atrophique ikoresheje inshinge za PRP autologique, no kugereranya iterambere ry’ibimenyetso hagati yitsinda rivura PRP nitsinda ryita ku barwayi bakoresheje itsinda rishinzwe kugenzura.Bitewe na rinite ya Atrophique isobanura ivuriro, hakenewe ubushakashatsi bwinshi kugirango tumenye uburyo bukora.Ariko, kugirango hirindwe igihombo cyimibereho nubukungu no kugabanuka kwimibereho yabarwayi, birakenewe gutanga ibisubizo byubushakashatsi hamwe ningaruka zo kuvura.
Nyamara, ubu bushakashatsi bufite aho bugarukira.Ubu bushakashatsi bwakozwe muburyo buteganijwe kandi ntibushobora gutegekwa kugenzurwa kuko bamwe mubitabiriye amahugurwa banze gahunda yo gutera amazuru.Ku bijyanye n’imyitwarire, ibikorwa byibasiye intego zinyigisho mu itsinda rishinzwe kugenzura bigomba guhagarikwa kurengera uburenganzira n’inyungu z’abarwayi.Kubwibyo, kugenera abarwayi ukurikije ibyo bakunda bituma ibisubizo byubushakashatsi bidakomera kurenza ibyatanzwe nubushakashatsi bwateganijwe.Byongeye kandi, rinite ya kabiri ya atrophique iterwa no guhindura no gukuraho imiterere yizuru ryambere.Gukora biopsy birashobora kongera atrophy.Kubwibyo, ukurikije imyitwarire, ntibishoboka gukora biopsy yamazuru ihuye nabarwayi barwaye rinite.Ibisubizo nyuma y'amezi 6 yo gukurikirana ntibishobora kwerekana ibisubizo birebire.Mubyongeyeho, umubare w'abarwayi bo mu itsinda ni muto.Kubwibyo, ubushakashatsi buzaza bugomba kubamo abarwayi benshi bakoresheje igishushanyo mbonera cyagenwe mugihe kirekire cyo gukurikirana.
Ibiri muri iyi ngingo byongeye gusubirwamo, kandi ntidutanga ingwate iyo ari yo yose cyangwa yerekana ko ari ukuri, kwiringirwa cyangwa kuzuza ibikubiye muri iyi ngingo, kandi ntabwo dushinzwe ibitekerezo by'iyi ngingo, nyamuneka ubyumve.）
Igihe cyo kohereza: Gicurasi-23-2023